Spray-dried extracts from Syzygium cumini seeds: physicochemical and biological evaluation

Revista Brasileira de Farmacognosia

Maria Paula G. Peixoto¹  Luís A. P. Freitas¹ 

[1] ,Universidade de São Paulo Faculdade de Ciências Farmacêuticas de Ribeirão Preto ,Brazil

关键词: Eugenia jambolana;    DPPH;    experimental diabetes;    flavonoids;    polyphenols;    spray-drying;   

DOI  :  10.1590/S0102-695X2012005000124

来源: SciELO

【 摘 要 】

Aqueous extract from seeds of Syzygium cumini (L.) Skeels, Myrtaceae, obtained by dynamic maceration was spray-dried and characterized by its physico-chemical and antihyperglycaemic action. The extract showed to possess high amount of polyphenols, significant in vitro free radical scavenger activity using the DPPH method and an antihyperglycaemic effect in alloxan-induced experimental diabetes. S. cumini spray-dried extracts were obtained using silicon dioxide and cassava starch as adjuvants. The powders showed acceptable flowability, compactability, and low hygroscopicity at 43% relative humidity. Besides, the spray-dried extracts showed in vivo antihyperglycaemic and in vitro scavenger activity comparable to the lyophilized extract. Thus, experimental data indicates that the extract from S. cumini has a relevant activity and that spray-drying could be adequately used to perform the technological processing of S. cumini fluid extracts.

【 授权许可】

CC BY-NC-ND   
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