Chemical constituents of Lecythis pisonis and cytotoxic activity

Revista Brasileira de Farmacognosia

Jocélia P. C. Oliveira²  Éverton L. F. Ferreira²  Mariana H. Chaves²  Gardenia C. G. Militão²  Gerardo M. V. Júnior¹  Arenice De M. Costa¹  Cláudia Do Ó Pessoa¹  Manoel O. De Moraes¹  Letícia V. Costa-lotufo¹ 

[1] ,Universidade Federal do Piauí,Brazil

关键词: Lecythis pisonis;    Lecythidaceae;    triterpenes;    cytotoxicity;   

DOI  :  10.1590/S0102-695X2012005000053

来源: SciELO

【 摘 要 】

The phytochemical investigation of the ethanol extract from leaves of Lecythis pisonis Cambess., Lecythidaceae, resulted in the isolation of seven triterpenes: α- and β-amyrin, uvaol and erythrodiol, ursolic and oleanolic acids and 3β-friedelinol, as well as a mixture of sitosterol and stigmasterol steroids and a diterpene (E)-phytol. The structures of these compounds were identified by¹H and 13C NMR spectral analysis and compared with literature data. The mixture of triterpenes ursolic and oleanolic acids isolated from the active ethereal fraction showed moderate cytotoxic activity. This paper describes for the first time the phytochemical and cytotoxic study of Lecythis pisonis' leaves.

【 授权许可】

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