Chemical composition and antimicrobial activity of Hedyosmum brasiliense Miq., Chloranthaceae, essential oil

Revista Brasileira de Farmacognosia

Karoline Kirchner²  Alberto Wisniewski Jr¹  Alexandre Bella Cruz²  Maique W. Biavatti¹  Daisy J. A. Netz² 

[1] ,Universidade do Vale do Itajaí Curso de Farmácia Núcleo de Investigações Químico-FarmacêuticasItajaí-SC,Brazil

关键词: Hedyosmum brasiliense;    Chloranthaceae;    essential oil;    antimicrobial activity;    Hedyosmum brasiliense;    Chloranthaceae;    óleo essencial;    atividade antimicrobiana;   

DOI  :  10.1590/S0102-695X2010005000005

来源: SciELO

【 摘 要 】

Hedyosmum brasiliense Miq., Chloranthaceae, is an endemic species of Brazil, locally known as "cidrão". Although H. brasiliense is popularly used as sedative, chemical constituents of this species remains uncharacterized. This work presents the essential oil composition, obtained by distillation of the fresh leaves and from a stored sample for three months, analysed by GC-FID and GC-MS. The inhibitory effects of essential oil were tested by the agar dilution method against six bacterial species (Bacillus subtilis, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus and S. saprophyticus). In addition, six fungal species (Candida albicans, C. parapsilosis, Microsporum canis, M. gypseum, Trichophyton rubrum and T. mentagrophytes) were included. Among the determined constituents, α-terpineol (10.2%), curzerene (8.9%), pinocarvone (8.4%) and β-thujene (7.1%) were found as the main components. The essential oil has only low activity against Gram-negative microorganisms. However, is remarkable active against Gram-positive bacteria and fungi with MIC values ranging from 0.125 to 2.5% (v/v).

【 授权许可】

CC BY-NC-ND   
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