A proposal for the quality control of Tanacetum parthenium (feverfew) and its hydroalcoholic extract

Revista Brasileira de Farmacognosia

Juliana Siqueira Chaves¹  Fernando Batista Da Costa¹ 

[1] ,Universidade de São Paulo Faculdade de Ciências Farmacêuticas de Ribeirão Preto Departamento de Ciências FarmacêuticasRibeirão Preto SP ,Brazil

关键词: Tanacetum parthenium;    Asteraceae;    quality control;    HPLC quantification;    hydroalcoholic extract;    flavonoids;    parthenolide;    Tanacetum parthenium;    Asteraceae;    controle de qualidade;    quantificação por CLAE;    extrato hidroalcoólico;    flavonóides;    partenolídeo;   

DOI  :  10.1590/S0102-695X2008000300009

来源: SciELO

【 摘 要 】

In this study, we present a proposal for the physical and chemical quality control of the powder of the species T. parthenium (feverfew) and its hydroalcoholic extract obtained by percolation. The sesquiterpene lactone parthenolide, the main active compound of this plant, was quantified by HPLC and its content was found to be 0.49% in the powder and 1.06% in the extract. The total content of flavonoids, determined by UV spectroscopy, was found to be 0.54% in the powder and 1.05% in the hydroalcoholic extract. Santin, the main flavonoid of this species, was isolated and further identified in the extract by HPLC. Since parthenolide can also be found in other Asteraceae species, the analysis of santin is important to certify the authenticity of the plant material. The results confirmed the authenticity of the plant material and the efficiency of the extraction procedure.

【 授权许可】

CC BY-NC-ND   
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