Use of alloplastic meshes in abdominal wounds of rats with induced peritonitis

ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)

Rafael Calvão Barbuto¹  Ivana Duval-araujo¹  Sumara Marques Barral¹  Raphael Grossi Rocha¹  Cristiane De Souza Bechara¹  Alfredo José Afonso Barbosa¹ 

关键词: Wound healing;    Peritonitis;    Hernia;    Surgical mesh;    Abdominal wall;    Cicatrização;    Peritonite;    Hérnia;    Tela cirúrgica;    Parede abdominal;   

DOI  :  10.1590/S0102-67202014000100007

来源: SciELO

【 摘 要 】

Background : The use of alloplastic meshes has been historically contra-indicated in patients with infection.Aim : To evaluate the use of polypropylene meshes in the treatment of abdominal wall defects in rats with peritonitis.Methods : Twenty Wistar female rats were divided into two groups: induction of peritonitis (test group) and without peritonitis (control group). An abdominal wall defect was created in all animals, and polypropylene mesh was applied. The evaluation of the tensile strength of the mesh was carried out using tensiometer and microscopic analysis of the healing area was done.Results : More adhesion of the mesh to the rat abdominal wall was observed in test group. The histopathological analyses showed prevalence of moderate to accentuated granulation tissue in both groups, without significant differences.Conclusion : The use of the mesh coverage on abdominal wall defects of rats with induced peritonitis did not show worse results than its use in healthy animals, nor was its integration to the resident tissue any worse.

【 授权许可】

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