Evaluation of patients with schistosomal portal hypertension treated in a tertiary hospital

ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)

Fábio Ferrari Makdissi¹  Paulo Herman¹  Renata Potonyacz Colaneri¹  Barbara Dos Santos Nunes¹  Vincenzo Pugliese¹  Roberto De Cleva¹  William A. Saad¹  Luiz Augusto Carneiro D`albuquerque¹  Ivan Cecconello¹ 

关键词: Schistosoma mansoni;    Portal hypertension;    Esophageal varices;    Upper gastrointestinal bleeding;    Schistosoma mansoni;    Hipertensão portal;    Varizes esofágicas;    Hemorragia digestiva;   

DOI  :  10.1590/S0102-67202009000400006

来源: SciELO

【 摘 要 】

BACKGROUND: Schistosomiasis is an important public health issue in more than 70 countries around the world. About 600 million people are at risk to acquire the parasite and there are 200 million infected worldwide. AIM: To evaluate the characteristics of schistosomal portal hypertension individuals who underwent previous esophageal varices bleeding treated in a tertiary hospital. METHODS: The records of 155 patients were evaluated and clinical, laboratorial, endoscopic, epidemiological features and hemorrhagic event severity were analyzed to individualize this population. RESULTS: Mean age was 37.2 years and no clinical signs of hepatic failure were observed. Serum laboratory tests to evaluate liver function were normal or slightly alter. Anemia was present in 70 %, leucopenia in 75 % and thrombocytopenia in 86 % of the patients. At endoscopic evaluation varices were classified as grade III and IV in 91.3 %; red spots were observed in 40.3 % and congestive gastropathy in 13.6 %. Patients presented a mean of 2.8 previous episodes of variceal hemorrhage and, in 75 % with hemodynamic instability. CONCLUSIONS: Patients with schistosomal portal hypertension and history of upper digestive bleeding from esophageal varices are young individuals, without either clinical or laboratorial evidence of liver dysfunction, that present high morbidity due to the severity of the acute event of bleeding.

【 授权许可】

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