Cost-effectiveness of prevention strategies for American tegumentary leishmaniasis in Argentina

Cadernos de Saúde Pública

Pablo Wenceslao Orellano²  Nestor Vazquez¹  Oscar Daniel Salomon² 

[1] ,Instituto Nacional de Medicina TropicalPuerto Iguazu,,Argentina

关键词: Leishmaniasis;    Disease Prevention;    Cost-Effectiveness Evaluation;    Leishmaniose;    Prevenção de Doenças;    Avaliação de Custo-Efetividade;    Leishmaniasis;    Prevención de Enfermedades;    Avaliación de Costo-Efectividad;   

DOI  :  10.1590/0102-311X00172512

来源: SciELO

【 摘 要 】

The aim of this study was to estimate the cost-effectiveness of reducing tegumentary leishmaniasis transmission using insecticide-impregnated clothing and curtains, and implementing training programs for early diagnosis. A societal perspective was adopted, with outcomes assessed in terms of costs per disability adjusted life years (DALY). Simulation was structured as a Markov model and costs were expressed in American dollars (US$). The incremental cost-effectiveness ratio of each strategy was calculated. One-way and multivariate sensitivity analyses were performed. The incremental cost-effectiveness ratio for early diagnosis strategy was estimated at US$ 156.46 per DALY averted, while that of prevention of transmission with insecticide-impregnated curtains and clothing was US$ 13,155.52 per DALY averted. Both strategies were more sensitive to the natural incidence of leishmaniasis, to the effectiveness of mucocutaneous leishmaniasis treatment and to the cost of each strategy. Prevention of vectorial transmission and early diagnosis have proved to be cost-effective measures.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License