Environment, interactions between Trypanosoma cruzi and its host, and health

Cadernos de Saúde Pública

Antonio R. L. Teixeira¹  Clever Gomes¹  Silene P. Lozzi¹  Mariana M. Hecht¹  Ana De Cássia Rosa¹  Pedro S. Monteiro¹  Ana Carolina Bussacos¹  Nadjar Nitz¹  Concepta Mcmanus¹ 

[1] ,Universidade de Brasília Faculdade de Medicina Brasília,Brasil

关键词: Trypanosoma cruzi;    Chagas Disease;    Host-Parasite Interactions;    Environment;    Trypanosoma cruzi;    Doença de Chagas;    Interações Hospedeiro-Parasita;    Meio Ambiente;   

DOI  :  10.1590/S0102-311X2009001300004

来源: SciELO

【 摘 要 】

An epidemiological chain involving Trypanosoma cruzi is discussed at the environmental level, and in terms of fine molecular interactions in invertebrate and vertebrate hosts dwelling in different ecosystems. This protozoan has a complex, genetically controlled plasticity, which confers adaptation to approximately 40 blood-sucking triatomine species and to over 1,000 mammalian species, fulfilling diverse metabolic requirements in its complex life-cycle. The Tr. cruzi infections are deeply embedded in countless ecotypes, where they are difficult to defeat using the control methods that are currently available. Many more field and laboratory studies are required to obtain data and information that may be used for the control and prevention of Tr. cruzi infections and their various disease manifestations. Emphasis should be placed on those sensitive interactions at cellular and environmental levels that could become selected targets for disease prevention. In the short term, new technologies for social mobilization should be used by people and organizations working for justice and equality through health information and promotion. A mass media directed program could deliver education, information and communication to protect the inhabitants at risk of contracting Tr. cruzi infections.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License