Impact of the Haemophilus influenzae type b vaccination program on HIB meningitis in Brazil

Cadernos de Saúde Pública

Sybelle De Souza Castro Miranzi²  Suzana Alves De Moraes¹  Isabel Cristina Martins De Freitas¹ 

[1] ,Universidade Federal do Triângulo Mineiro Departamento de Medicina Social Uberaba,Brasil

关键词: Haemophilus influenzae;    Bacterial Meningitis;    Vaccination;    Time Series Studies;    Haemophilus influenzae;    Meningite Bacteriana;    Vacinação;    Estudos de Séries Temporais;   

DOI  :  10.1590/S0102-311X2007000700021

来源: SciELO

【 摘 要 】

This study aimed to evaluate the impact of vaccination against Haemophilus influenzae type b (HIB) in Brazil on the morbidity, mortality, and case fatality of HIB meningitis, using the Ministry of Health database and population data from the Brazilian Institute of Geography and Statistics (Instituto Brasileiro de Geografia e Estatística - IBGE). Impact was evaluated through a time series analysis (1983-2002), using regression forecasting (RF) by dividing the time series into two periods: (a) historical (1983-1998) and (b) validation (1999-2002). Impact of the vaccination was positive, although more significant for incidence and mortality than for case fatality rates.

【 授权许可】

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