Uso de medicamentos como fator de risco para fratura grave decorrente de queda em idosos

Cadernos de Saúde Pública

Evandro Da Silva Freire Coutinho²  Sidney Dutra Da Silva¹ 

[1] ,Fundação Oswaldo Cruz Escola Nacional de Saúde Pública Departamento de Epidemiologia e Métodos Quantitativos em SaúdeRio de Janeiro RJ ,Brasil

关键词: Fractures;    Drugs;    Aging Health;    Accidental Falls;    Fraturas;    Medicamentos;    Saúde do Idoso;    Acidentes por Quedas;   

DOI  :  10.1590/S0102-311X2002000500029

来源: SciELO

【 摘 要 】

Falls leading to fractures among the elderly are a major public problem. A case-control study was conducted on the use of certain drugs as a risk factor for hospitalization due to fractures after falls among individuals aged 60 years or over in the city of Rio de Janeiro, Brazil. One hundred sixty-nine cases and 315 in-patient controls were matched by age, sex, and hospital. Odds ratios (OR) adjusted for potential confounders were calculated using conditional logistic regression. Increased risk of such accidents was found for calcium channel antagonists (OR = 1.96, 1.16-3.30) and benzodiazepines (OR = 2.09, 1.08-4.05), and decreased risk was associated with diuretics (OR = 0.40, 0.20-0.80). Antacids, digitalis, and laxatives were associated with reduced risk of fractures after falls that reached borderline statistical significance (0.05 < p < 0.10). The findings highlight the need to weigh risks and benefits of medication in the elderly. It is also important to advise such individuals and their families on how to avoid falls when such medication proves necessary.

【 授权许可】

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