Endocrine disruptors and congenital anomalies

Cadernos de Saúde Pública

Mônica Rittler²  Eduardo E. Castilla¹ 

[1] ,Hospital Materno Infantil Ramon SardáBuenos Aires,Argentina

关键词: Sex Ratio;    Hypospadia;    Cryptorchidism;    Testicular Neoplasms;    Endocrine Disruptors;    Razão de Masculinidade;    Hipospadia;    Criptorquidismo;    Neoplasias Testiculares;    Desreguladores Endócrinos;   

DOI  :  10.1590/S0102-311X2002000200006

来源: SciELO

【 摘 要 】

The specialized literature was reviewed concerning the suspected increasing secular trends in the frequency of female births, male genital congenital anomalies, abnormal sperm counts, and testicular cancer. Although no risk factors could be identified yet, the observed sex ratio decline during the last decades has been considered to be an effect of certain pollutants on normal hormone activity, and human reproductive development. Reported increasing trends in the frequencies of hypospadias and cryptorchidism are very difficult to be interpreted due to the large variability in the registered frequency of these malformations due to operational as well as biological reasons.

【 授权许可】

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