Multiobjective approach in plans for treatment of cancer by radiotherapy

Pesquisa Operacional

Thalita Monteiro Obal¹  Neida Maria Patias Volpi¹  Simone Aparecida Miloca¹ 

[1] ,Universidade Federal do Paraná,Brazil

关键词: 3D conformal radiotherapy;    multiobjective programming;    method of weighted function;   

DOI  :  10.1590/S0101-74382013000200008

来源: SciELO

【 摘 要 】

Nowadays the technique of radiotherapy has been one of the main alternatives for the treatment of several types of cancer today. With technological development, especially in the case of 3D conformal radiotherapy, applications involving mathematical techniques and algorithms have been proposed to help the development a good treatment plan. This paper aims at present a model for multiobjective linear programming problem of dose intensity. The focus of the model is to determine the best dose distribution of radiation field, so that the dose delivered to the tumor to be prescribed and that affects the minimum the noble and healthy tissues. A test case of prostate cancer was used as an example of the numerical model and the Pareto-Optimal Frontier was generated using the method of weighted function.

【 授权许可】

CC BY   
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