Pain determinants of pain in autosomal dominant polycystic kidney disease

Jornal Brasileiro de Nefrologia

José Luiz Nishiura¹  Samara Rodrigues Moreira Eloi¹  Ita Pfeferman Heilberg¹ 

[1] ,Universidade Federal de São Paulo

关键词: abdominal pain;    lumbar pain;    nephrolithiasis;    polycystic kidney disease;    doença renal policística;    dor abdominal;    dor lombar;    nefrolitíase;   

DOI  :  10.5935/0101-2800.20130038

来源: SciELO

【 摘 要 】

Pain is the most common symptom reported by ADPKD patients, afflicting approximately 60% of cases and may result from renal hemorrhage, calculi, urinary tract infections, cyst rupture, or due to stretching of the capsule or traction of the renal pedicle. We have recently investigated pain patterns in AD-PKD patients using a translated version of a pain questionnaire specific for AD-PKD population. The questionnaire revealed that 67% patients with ADPKD exhibited some type of pain. The findings of that study emphasized that pain appeared early in the course of ADPKD, when patients still exhibited preserved renal function. In the present study, a multivariate logistic regression analysis disclosed that renal volume (9-fold increased risk) and nephrolithiasis (4-fold increased risk) were the most important determinant factors for pain in ADPKD patients with preserved renal function, after adjustments for the presence of hypertension and duration of the disease.

【 授权许可】

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