Citotoxicity of food dyes sunset yellow (E-110), bordeaux red (E-123), and tatrazine yellow (E-102) on Allium cepa L. root meristematic cells

Food Science and Technology (Campinas)

Keiva Maria Silva Gomes¹  Maria Virna Gonçalves Aguiar De Oliveira¹  Francisco Ronielson De Sousa Carvalho¹  Camila Carvalho Menezes¹  Ana Paula Peron¹ 

[1] ,Universidade Federal do Piauí Laboratório de Citogenética Vegetal e Animal Núcleo de Pesquisa Aplicada a Saúde e ao Meio-ambientePicos PI ,Brasil

关键词: food additive;    cytotoxicity;    Allium cepa;    aditivo alimentar;    citotoxicidade;    Allium cepa;   

DOI  :  10.1590/S0101-20612013005000012

来源: SciELO

【 摘 要 】

The objective of this study was to evaluate the cytotoxic effect of the food dyes sunset yellow, bordeaux red, and tartrazine yellow on the cellular cycle of Allium cepa L. Each dye was evaluated at the doses of 0.4 and 4.0 mL, at the exposure times of 24 and 48 hours in root tip cells of Allium cepa L. Slides were prepared and cells were analyzed during the whole cell cycle for cellular aberrations totaling 5,000 total cells for each dose evaluated. The mitotic index was calculated, and statistical analysis was performed using the Chi-squared test (p < 0.05). The results showed that the three dyes used under the evaluated doses and exposure times were cytotoxic to the cells of the system-test used. Further cytotoxicity studies should be conducted for additional results and a proper evaluation of the effect of these three dyes on a cellular level.

【 授权许可】

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