Effects of defatted amaranth (Amaranthus caudatus L.) snacks on lipid metabolism of patients with moderate hypercholesterolemia

Food Science and Technology (Campinas)

Rosa Nilda Chávez-jáuregui²  Raul Dias Santos¹  Alessandra Macedo¹  Ana Paula Marte Chacra²  Tania Leme Martinez²  José Alfredo Gomes Arêas² 

[1],Universidade de São Paulo Faculdade de Saúde Pública Departamento de NutriçãoSão Paulo SP ,Brazil

关键词: cholesterol;    amaranth;    functional food;    HDL-c;    dislipidemia;    colesterol;    amaranto;    alimento funcional;    HDL-col;    dislipidemia;   

DOI  :  10.1590/S0101-20612010000400026

来源: SciELO

【 摘 要 】

We evaluated the effects of defatted amaranth (Amaranthus caudatus L.) snacks on plasma lipids in moderate hypercholesterolemic patients. Twenty-two subjects [30-65 years old), 11 males, with total cholesterol (TC) > 240 mg.dL-1, low-density cholesterol (LDL-c) 160-190 mg.dL-1 and plasma triglycerides (TG) < 400 mg.dL-1] were randomized in a double blind clinical trial to receive an amaranth snack (50 g/day) or equivalent corn snack (placebo) for 2 months. There were no differences between amaranth and placebo on TC and LDL-c, and TG respectively: -8.4 and -5.7% (p = 0.17); -12.3 and -9.7% (p = 0.41) and -0.6 and -7.3% (p = 0.47). However, amaranth snacks significantly reduced high-density cholesterol (HDL-c): -15.2 vs. -4% (p = 0.03). In conclusion, the intake of 50 g of extruded amaranth daily during 60 days did not significantly reduce LDL-c in moderate hypercholesterolemic subjects; furthermore there was a significant reduction in HDL-c. Studies with greater number of subjects and greater quantity of this food are necessary to test the effects of amaranth on lipid metabolism in humans.

【 授权许可】

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