A conceptual and practical overview of cDNA microarray technology: implications for basic and clinical sciences

Brazilian Journal of Medical and Biological Research

V. De Mello-coelho¹  K.l. Hess¹ 

[1],Universidade Federal do Rio de Janeiro Instituto de Ciências Biomédicas Departamento de Histologia e EmbriologiaRio de Janeiro RJ ,Brasil

关键词: Biotechnology;    cDNA microarray;    Gene expression;    Genomics;   

DOI  :  10.1590/S0100-879X2005001000011

来源: SciELO

【 摘 要 】

cDNA microarray is an innovative technology that facilitates the analysis of the expression of thousands of genes simultaneously. The utilization of this methodology, which is rapidly evolving, requires a combination of expertise from the biological, mathematical and statistical sciences. In this review, we attempt to provide an overview of the principles of cDNA microarray technology, the practical concerns of the analytical processing of the data obtained, the correlation of this methodology with other data analysis methods such as immunohistochemistry in tissue microarrays, and the cDNA microarray application in distinct areas of the basic and clinical sciences.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License