期刊论文详细信息
Brazilian Journal of Medical and Biological Research
Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system
A.c. Deslandes2  H. Veiga2  M. Cagy1  R. Piedade2  F. Pompeu1  P. Ribeiro2 
[1] ,Universidade Federal do Rio de Janeiro Instituto de Psiquiatria Setor de Mapeamento Cerebral e Integração Sensório-MotoraRio de Janeiro RJ ,Brasil
关键词: Quantitative electroencephalography;    P300;    Caffeine;    Cognitive and motor measures;    Psychostimulants;   
DOI  :  10.1590/S0100-879X2005000700011
来源: SciELO
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【 摘 要 】

Caffeine is the most consumed psychoactive substance in the world. The effects of caffeine have been studied using cognitive and motor measures, quantitative electroencephalography (qEEG) and event-related potentials. However, these methods are not usually employed in combination, a fact that impairs the interpretation of the results. The objective of the present study was to analyze changes in electrophysiological, cognitive and motor variables with the ingestion of caffeine, and to relate central to peripheral responses. For this purpose we recorded event-related potentials and eyes-closed, resting EEG, applied the Stroop test, and measured reaction time. Fifteen volunteers took caffeine (400 mg) or placebo in a randomized, crossover, double-blind design. A significant reduction of alpha absolute power over the entire scalp and of P300 latency at the Fz electrode were observed after caffeine ingestion. These results are consistent with a stimulatory effect of caffeine, although there was no change in the attention (Stroop) test or in reaction time. The qEEG seems to be the most sensitive index of the changes produced by caffeine in the central nervous system since it proved to be capable of detecting changes that were not evident in the tests of cognitive or motor performance.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License

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