Distribution of biglycan and decorin in rat dental tissue

Brazilian Journal of Medical and Biological Research

D.m.h. Tenório¹  M.f. Santos¹  T.m.t. Zorn¹ 

[1] ,Universidade de São Paulo Instituto de Ciências Biomédicas I Departamento de Histologia e EmbriologiaSão Paulo SP ,Brasil

关键词: Decorin;    Biglycan;    Odontoblasts;    Predentin;    Immunohistochemistry;   

DOI  :  10.1590/S0100-879X2003000800012

来源: SciELO

【 摘 要 】

Biglycan and decorin are small leucine-rich proteoglycans that play several biological and structural roles in different tissues and organs. Several reports have indicated that biglycan participates in odontoblast and ameloblast differentiation and in the calcification process. In the present study we show that the expression of biglycan changes from within the ameloblasts and odontoblasts to the extracellular space according to the stage of animal development. In predentin and in the pulp space, however, biglycan was continually expressed throughout the period of investigation. In contrast, decorin was absent in odontoblasts and in ameloblasts and was exclusively expressed in predentin throughout the period of observation. In young rats, however, decorin was expressed in the extracellular spaces of the pulp, where it was concentrated mainly in the peripheral pulp.

【 授权许可】

CC BY   
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