Expression and cytokine secretion in the states of immune reactivation in leprosy

Brazilian Journal of Medical and Biological Research

E.p. Sampaio¹  E.n. Sarno¹ 

[1] ,FIOCRUZ

关键词: eprosy;    reactions;    cytokines;   

DOI  :  10.1590/S0100-879X1998000100009

来源: SciELO

【 摘 要 】

Leprosy is a chronic inflammatory disease caused by Mycobacterium leprae. The human response to this pathogen exhibits intriguing aspects which are up to now not well understood. The present study discusses the probable mechanisms involved in T cell-specific unresponsiveness observed in lepromatous patients. Analysis of the cytokine profile either in blood leukocytes or in skin specimens taken from leprosy lesions indicates that some parameters of Th1 immune response are present in lepromatous patients under reactional states

【 授权许可】

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