Elimination of the tremorgenic toxin of Ipomoea asarifolia by milk

Pesquisa Veterinária Brasileira

José Radmácyo G. Lopes²  Franklin Riet-correa²  Daniel Cook¹  James A. Pfister¹  Rosane M.t. Medeiros² 

[1] ,Universidade Federal Universidade Federal de Campina Grande Hospital Veterinário Patos PB ,Brazil

关键词: Poisonous plants;    Ipomoea asarifolia;    tremorgenic toxins;    toxins in milk;    plant poisoning;    Plantas tóxicas;    Ipomoea asarifolia;    toxinas tremorgênica;    toxinas no leite;    plantas tóxicas;   

DOI  :  10.1590/S0100-736X2014001100009

来源: SciELO

【 摘 要 】

With the aim to determine if the tremorgenic toxin of Ipomoea asarifolia is eliminated in milk, three groups of Swiss female mice received, immediately after giving birth until weaning, a ration containing 20% or 30% of dry I. asarifolia. All the offspring of the females that received 20% or 30% I. asarifolia showed tremors 2-4 days after birth. The offspring of the females that received 20% I. asarifolia recovered 4-7 days after weaning. The offspring of the females that received 30% of the plant in the ration died while showing tremors before weaning or up to two days after weaning. It is concluded that the tremorgenic compound of I. asarifolia or its toxic metabolites are eliminated in milk, and that lactating mice may be used as a model for the determination of the toxic compound(s) in this plant.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License