Necrotizing enteritis associated with Clostridium perfringensType B in chinchillas (Chinchilla lanigera)

Pesquisa Veterinária Brasileira

Ricardo B. Lucena²  Luana Farias²  Felipe Libardoni²  Agueda C. Vargas²  Paula R. Giaretta¹  Claudio S. L. Barros² 

[1] ,Universidade Federal de Santa MariaSanta Maria RS ,Brazil

关键词: Diseases of chinchilla;    pathology;    Clostridium perfringens;    enterotoxemia;    intestinal infection;    Doenças de chinchilas;    patologia;    Clostridium perfringens;    enterotoxemia;    infecção intestinal;   

DOI  :  10.1590/S0100-736X2011001200006

来源: SciELO

【 摘 要 】

Four 3-4 month-old chinchillas (Chinchilla lanigera) from a commercial flock of 395 chinchillas, were found dead with evidence of previous diarrhea and prolapsed rectum. A fifth 8 month-old chinchilla died 8 hours after being found recumbent, apathetic, diarrheic and with a prolapsed rectum. Two chinchillas were necropsied and observed gross lesions consisted of extensive hemorrhagic enteritis, mild pulmonary edema and enlarged and yellow liver; this latter finding was particularly prominent in the chinchilla presenting longer clinical course. Histologically there was necrotizing enteritis associated with abundant bacterial rods aggregates in the intestinal surface epithelium and within the lamina propria. In the lungs there were small amounts of pink proteinaceous material (edema) in the interstitium and marked vacuolar hepatocellullar degeneration (lipidosis) in the liver. Anaerobic cultures from the intestinal contents of one of the affected chinchillas yielded Clostridium perfringens. Genotyping of this C. perfringens isolate was achieved by multiplex polymerase chain reaction (mPCR) as C. perfringenstype B due to detection of alpha, beta and epsilon-toxin genes. These findings suggest C. perfringens type B as an important cause of sudden or acute death in chinchillas.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License