Acute toxicity and histopathological alterations of Roundup® herbicide on "cachama blanca" (Piaractus brachypomus)

Pesquisa Veterinária Brasileira

Wilson F. Ramírez-duarte¹  Iang S. Rondón-barragán¹  Pedro R. Eslava-mocha¹ 

[1] ,Universidad de los Llanos Instituto de Acuicultura Villavicencio Meta ,Colombia

关键词: Roundup®;    glyphosate;    acute toxicity;    histopathology;    Piaractus brachypomus;    Roundup®;    glifosato;    toxicidade aguda;    histopatologia;    Piaractus brachypomus;   

DOI  :  10.1590/S0100-736X2008001100002

来源: SciELO

【 摘 要 】

Acute toxicity of the glyphosate -N (phosphonomethyl) glycine- herbicide, Roundup®, in juveniles of cachama blanca, (Piaractus brachypomus), was evaluated and the histopathological lesions were assessed. The 96 h lethal concentration 50 was 97.47mg.L-1 (P<0.05). In the gill, necrotic and proliferative lesions were detected. In the liver, congestion, degenerative foci, hyaline droplets and lipidic vacuolization of the hepatocytes were observed. In the stomach mild hyperplasia of mucous cells was detected, which was also observed in the skin. In this latter tissue, a large increase in the thickness of the epidermis with necrotic lesions, infiltration of leukocytes and melanin pigment were observed. In the brain, degenerative foci of neuronal bodies in the telencephalon associated with gliosis and infiltration of eosinophilic granule cells/mast cells were shown. In conclusion, gills, liver, skin and brain are susceptible to Roundup®. Moreover, effects on the central nervous system could affect olfaction as well as individual and group behavior, the reproductive performance of the fish and hence have repercussions at the population level.

【 授权许可】

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