Intestinal lesions in pigs affected with postweaning multisystemic wasting syndrome

Pesquisa Veterinária Brasileira

Priscila Zlotowski²  André M.r. Corrêa²  David E.s.n. Barcellos¹  Cláudio E.f. Cruz²  William Asanome¹  Aline Fernandes Barry¹  Amauri Alcindo Alfieri¹  David Driemeier² 

[1] ,Universidade Federal do Rio Grande do Sul Faculdade de Medicina Veterinária Departamento de Patologia Clinica VeterináriaPorto Alegre RS ,Brazil

关键词: Circovirus;    co-infections;    enteric lesions;    PCV2;    PMWS;    Circovírus;    co-infecções;    lesões entéricas;    PCV2;    SMDS;   

DOI  :  10.1590/S0100-736X2008000600009

来源: SciELO

【 摘 要 】

Samples of mesenteric lymph nodes and intestines from 79 unthrifty 3- to 5-month-old postweaning pigs, confirmed as naturally affected with postweaning multisystemic wasting syndrome (PMWS), were studied. Pigs originated from 12 farms in southern Brazil and were selected on the basis of clinical signs and/or gross lesions suggestive of enteric disorder. Lymphohistiocytic infiltrates of varying intensity were associated with anti-porcine circovirus type 2 (anti-PCV2) immunostaining (IS) in samples of intestines and mesenteric lymph nodes from all pigs. Although most findings were similar to those described in PCV2-associated enteritis, anti-PCV2 IS in association with depletion of the goblet cell mucin stores (24 pigs), diffuse ileal villous atrophy and fusion (18 pigs), and dilatation of the lymphatic vessels (11 pigs) combined or not with lymphangitis were also observed. PCV2 antigen was immunohistochemically demonstrated in the cytoplasm and nuclei from intralesional epithelial cells, histiocytes, and endothelial-like cells in intestinal tissues. Together these findings imply an association with PCV2. The presence of co-infections by Lawsonia intracellularis, Brachyspira spp., Mycobacterium spp., Salmonella spp., rotavirus, parvovirus, coronavirus and enteric calicivirus with PCV2 in the intestinal lesions was investigated.

【 授权许可】

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