ACETANILIDA: SÍNTESE VERDE SEM SOLVENTE

Química Nova

Silvio Cunha¹  Otelício Bispo Dos Santos Da Costa¹  Lourenço Luis Botelho De Santana¹  Wilson Araújo Lopes¹ 

关键词: green chemistry;    acetanilide;    aniline;    undergraduate organic chemistry experiment;    solventless reaction;   

DOI  :  10.5935/0100-4042.20150080

来源: SciELO

【 摘 要 】

We described herein a solvent-free synthesis of acetanilide developed in the context of green chemistry. The synthetic approach consisted of the reaction of aniline with acetic anhydride without additives, while using smaller amounts of reagents and water than previously described for this undergraduate experiment. The E Factor was 0.6 by experienced chemists and 0.9 by students.

【 授权许可】

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