CHEMICAL CONSTITUENTS FROM THE STEM BARK OF Annona pickelii (Annonaceae)

Química Nova

Emmanoel Vilaça Costa¹  Marília Fernanda Chaves Sampaio¹  Marcos José Salvador¹  Angelita Nepel¹  Andersson Barison¹ 

关键词: Annonaceae;    Annona pickelii;    steroids;    lignans;    alkaloids;    NMR;   

DOI  :  10.5935/0100-4042.20150069

来源: SciELO

【 摘 要 】

The phytochemical investigation of the stem bark of Annona pickelii yielded four steroids (β-sitostenone, β-sitosterol, stigmasterol and campesterol), three lignans (eudesmin, magnolin and yangambin), twelve alkaloids (liriodenine, lysicamine, atherospermidine, anonaine, analobine, asimilobine, discretamine, stepholidine, coclaurine, orientaline, juziphine and stepharine), and a benzenoid (2-methoxybenzoic acid). These compounds support their recent reclassification from Rollinia to Annona, and that it is a typical species of the family Annonaceae. Significant antifungal and antioxidant activities were found for the methanol crude extract as well as for the lignans eudesmin, magnolin, yangambin and the alkaloid discretamine. In addition, several items of NMR data for the alkaloids were reviewed and unequivocally described in this work.

【 授权许可】

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