Experimento didático de quimiometria para planejamento de experimentos: avaliação das condições experimentais na determinação espectrofotométrica de ferro II com o-fenantrolina. Um tutorial, parte III

Química Nova

Márcia Cristina Breitkreitz¹  André Marcelo De Souza¹  Ronei Jesus Poppi¹ 

[1] ,Universidade Estadual de Campinas Instituto de Química Departamento de Química AnalíticaCampinas SP ,Brasil

关键词: design of experiments;    multivariate optimization;    teaching experiment;   

DOI  :  10.5935/0100-4042.20140092

来源: SciELO

【 摘 要 】

The objective of this manuscript is to describe a practical experiment that can be employed for teaching concepts related to design of experiments using Matlab or Octave computing environment to beginners, undergraduate and graduate students. The classical experiment for determination of Fe (II) using o-phenanthroline was selected because it is easy to understand, and all the required materials are readily available in most analytical laboratories. The approach used in this tutorial is divided in two steps: first, the students are introduced to the concept of multivariate effects, how to calculate and interpret them, and the construction and evaluation of a linear model to describe the experimental domain by using a 2³ factorial design. Second, an extension of the factorial design by adding axial points is described, thereby, providing a central composite design. The quadratic model is then introduced and used to build the response surface.

【 授权许可】

CC BY-NC   
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