Preparação e caracterização do complexo de inclusão do óleo essencial de Croton zehntneri com β-ciclodextrina

Química Nova

Ulisses N. Aguiar²  Sidney G. De Lima²  Márcio S. Rocha²  Rivelilson Mendes De Freitas²  Talita M. Oliveira²  Raiane M. Silva¹  Lara C. B. Moura¹  Lorena T. G. De Almeida¹ 

[1] ,Universidade Federal do Piauí Departamento de Bioquímica e Farmacologia Teresina PI ,Brasil

关键词: Croton zehntneri;    essential oil;    β-cyclodextrin;   

DOI  :  10.1590/S0100-40422014000100010

来源: SciELO

【 摘 要 】

Croton zehntneri, a plant native to northeastern Brazil, is widely used in folk medicine to treat gastrointestinal problems and has rich essential oil content. The essential oil of C. Zehntneri was analyzed by GC-MS, and its inclusion complex with β-cyclodextrin (β-CD) was characterized by both vibrational spectroscopy and differential scanning calorimetry (DSC). Estragol was the major component identified in the essential oil by the study. IR spectra indicated an interaction of β-CD with essential oil from C. zehntneri, a finding corroborated by the stability constant and scanning calorimetry. Microencapsulation within β-CD has the potential to mask sensory attributes and increase aqueous solubility of oils, thereby improving their applicability as drugs.

【 授权许可】

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