Constituintes químicos e avaliação da atividade antibacteriana de Macroptilium lathyroides (L.) Urb. (Fabaceae)

Química Nova

Leôncio M. De Sousa²  Roberto W. Da S. Gois²  Telma L. G. Lemos²  Ângela M. C. Arriaga²  Manoel Andrade-neto²  Gilvandete M. P. Santiago¹  Raimundo Braz-filho¹  José G. M. Da Costa¹  Fabiola F. G. Rodrigues¹ 

[1] ,Universidade Federal do Ceará Departamento de Química Orgânica e Inorgânica Fortaleza CE ,Brasil

关键词: Macroptilium lathyroides;    lasiodiplodin derivatives;    coumaronochromone;   

DOI  :  10.1590/S0100-40422013000900016

来源: SciELO

【 摘 要 】

The chemical investigation of the stems and branches of Macroptilium lathyroides led to the isolation of a mixture of β-sitosterol and stigmasterol. The extracts from the roots allowed the isolation of lasiodiplodin, a mixture of stigmast-4-en-6β-ol-3-one and stigmast-4,22-dien-6β-ol-3-one, de-O-methyllasiodiplodin, genistein and lupinalbin A. The structures of the isolated compounds were assigned on the basis of their NMR data, including comparison of their spectral data with values described in the literature. The antibacterial activity of crude extracts from stems, branches and roots was evaluated. This is the first report involving the chemical investigation of this species.

【 授权许可】

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