Planejamento experimental na otimização da extração dos frutos de Syzygium cumini (L.) skeels

Química Nova

Ketylin Fernanda Migliato²  Marcos Antonio Corrêa²  Hérida Regina Nunes Salgado²  João Olimpio Tognolli¹  Luis Vitor S. Sacramento¹  João Carlos Palazzo De Mello¹  Maria José Soares Mendes Giannini¹  Ana Marisa Fusco Almeida¹  Antonio Carlos Pizzolitto¹ 

[1] ,Universidade Estadual Paulista Faculdade de Ciências Farmacêuticas Departamento de Fármacos e MedicamentosAraraquara SP ,Brasil

关键词: Syzygium cumini;    extraction method;    factorial design;   

DOI  :  10.1590/S0100-40422011000400024

来源: SciELO

【 摘 要 】

The aim of this study was to standardize the extractive solution of Syzygium cumini. The extractive solution was selected through a full factorial design, considering the extraction method (maceration-5-days, turbo extraction, percolation), extractor solvent (ethanol 50, 70, 96%) and plant material particle size 0.302 mm into a plant:solvent ratio (1:10), using the dried residue and antimicrobial activity determination as evaluation criteria. The tests were performed in triplicate. It appeared that the percolation is the best procedure extractive, and ethanol mixture: water (50:50) the best solvent. ANOVA analysis showed the importance of these parameters.

【 授权许可】

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