An expeditious and consistent procedure for tetrahydrofuran (THF) drying and deoxygenation by the still apparatus

Química Nova

Alessandro B. C. Simas¹  Vera L. P. Pereira¹  Cleber B. Barreto Jr.¹  Daniel L. De Sales¹  Leandro L. De Carvalho¹ 

[1] ,Universidade Federal do Rio de Janeiro Centro de Ciências da Saúd Núcleo de Pesquisas de Produtos NaturaisRio de Janeiro RJ ,Brasil

关键词: THF;    still apparatus;    purification;   

DOI  :  10.1590/S0100-40422009000900042

来源: SciELO

【 摘 要 】

Despite the availability of alternative methods for drying tetrahydrofuran (THF), the use of the still apparatus, wherein a THF solution containing Na-bezophenone ketyl is heated to reflux, remains widespread. We herein propose a set of procedures to solve the problems usually faced in applying this drying technique. Moreover, a discussion is made on the chemical knowledge underlying such procedures. Safety and economy issues concerned with the operation of the THF still apparatus are also discussed.

【 授权许可】

CC BY-NC   
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