Diterpenos casbanos e acetofenonas de Croton nepetaefolius (Euphorbiaceae)

Química Nova

Hélcio Silva Santos²  Francisca Maria Rodrigues Mesquita²  Telma Leda G. Lemos¹  Francisco Jose Queiroz Monte¹  Raimundo Braz-filho¹ 

[1] ,Universidade Estadual Vale do Acaraú Centro de Ciências Exatas e Tecnologia Sobral CE ,Brasil

关键词: casbane diterpenoid;    acetophenones;    Croton nepetaefolius;   

DOI  :  10.1590/S0100-40422008000300026

来源: SciELO

【 摘 要 】

Croton nepetaefolius is an aromatic plant native to the northeast of Brazil where it is extensively used in folk medicine as a sedative, orexigen and antispasmodic agent. The present work deals with the chromatographic analysis of the ethanolic extract of Croton nepetaefolius stalk. It allowed the isolation and characterization of two diterpenoids named 1,4-dihydroxy-2E,6E,12E-trien-5-one-casbane and 4-hydroxy-2E,6E,12E-5-one-casbane, two acetophenones named 2-hydroxy-4,6-dimethoxyacetophenone and 2-hydroxy-3,4,6-trimethoxyacetophenone and the steroids 3-O-b-D-glucopiranosylsitosterol and a mixture of b-sitosterol and stigmasterol. Structural elucidation was done on the basis of spectral data, mainly high field NMR and EIMS.

【 授权许可】

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