Lipossomas: a bala mágica acertou?

Química Nova

Nuno C. Santos²  Miguel A. R. B. Castanho¹ 

[1] ,Faculdade de Medicina de Lisboa Instituto de Bioquímica

关键词: liposome;    vesicle;    drug delivery;   

DOI  :  10.1590/S0100-40422002000700019

来源: SciELO

【 摘 要 】

Efficient drug delivery systems are as important as drug themselves. A powerful drug unable to reach the target cell is useless in practice. Ehrlich's Magic Bullet was the first carrier system to be proposed. The evolution in this domain has been quite slow as the natural mechanisms of mammals against foreign products are hard to overcome. However, lipid-based systems (liposomes and related vesicles) have attained reasonable success. The basic preparations and structural features of liposomes and related vesicles as well as their applications are addressed from the chemist's and biochemist's point of view.

【 授权许可】

CC BY-NC   
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