Estudos de proteção da célula de saccharomyces cerevisiae para utilização em reações de redução em meio orgânico

Química Nova

Maria Da Graça Nascimento²  Sandra Patricia Zanotto²  Sílvia Pedroso Melegari²  Paulo J. S. Moran¹ 

[1] ,Universidade Federal de Santa Catarina Departamento de Química Florianópolis SC

关键词: biotransformations;    baker's yeast;    enantioselective reduction;   

DOI  :  10.1590/S0100-40422002000400011

来源: SciELO

【 摘 要 】

New methodologies for protection of Saccharomyces cerevisiae (FP) cells when supported in montmorillonite K10 (K10), recovered or not with gelatin (G) and in the presence or absence of sucrose (S) are presented. These systems were used for the enantioselective reduction of ethyl acetoacetate and a-chloroacetophenone in hexane, under FP/K10/G/S and FP/S at 20ºC during 24 hours, affording S-(+)-ethyl-3-hydroxybutanoate in 100% conversion and 99% ee, and R-(-)-2-chloro-1-phenylethanol 79% and 78% ee at 20 and 30 ºC, respectivelly.

【 授权许可】

CC BY-NC   
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