Constituintes químicos isolados de simira glaziovii (K. schum) steyerm. e a atribuição dos deslocamentos químicos dos átomos de carbono e hidrogênio do alcalóide ofiorina e seus derivados

Química Nova

Ana Beatriz F. D' O. Bastos²  Mário Geraldo De Carvalho²  Javier Rincón Velandia²  Raimundo Braz-filho¹ 

[1] ,Universidade Federal Rural do Rio de Janeiro Instituto de Ciências Exatas Departamento de QuímicaSeropédica RJ

关键词: Simira glaziovii;    Rubiaceae;    steroids;    harmane;    (-)-ophiorine;   

DOI  :  10.1590/S0100-40422002000200012

来源: SciELO

【 摘 要 】

Chromatographic fractionation of bark extracts from Simira glaziovii (Rubiaceae) afforded the steroids beta-sitostenone, stigmastenone, beta-sitosterol and stigmasterol, methyl trans-4-hidroxy-3-methoxycinamate (1), the alkaloids harmane (2) and the new stereoisomer of ophiorine B (3). The structures were established by ¹H and 13C NMR, including 2D techniques and mass spectral analysis, of the natural products and pentaacetyllyalosidic acid (4a) and beta-carboline monoterpene tetraacetylglucoside (5, 1,22-lactamlyaloside) derivatives obtained by chemical transformations.

【 授权许可】

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