Estudo fitoquímico e avaliação do potencial antidiabético do Cissus sicyoides L. (Vitaceae)

Química Nova

Flávio Luís Beltrame²  Juliano Luis Sartoretto²  Roberto Barbosa Bazotte²  Roberto Nakamura Cuman²  Diógenes Aparício Garcia Cortez²  Luiz Claudio Fernandes¹  Osvaldo Tchaikovski¹ 

[1] ,Universidade Estadual de Maringá Departamento de Farmácia e Farmacologia Maringá PR

关键词: Cissus sicyoides;    Vitaceae;    antidiabetic potential;    flavonoids;   

DOI  :  10.1590/S0100-40422001000600014

来源: SciELO

【 摘 要 】

The effect of hydroalcoholic extracts (HE) obtained from leaves of Cissus sicyoides (CS) on glucose tolerance (GT) was investigated in rats treated with dexametasone (DEX). Our results showed that HE intensified the decreased GT promoted by (DEX). Additionally, the flavonoids kaempferol 3-O-rhamnoside and quercetin 3-O-rhamnoside, obtained from aerial parts of CS, were used to study the incorporation of glucose to glycogen in soleo muscle. The results showed that both flavonoids did not show effect on glycogen synthesis. Thus, our data, in contrast to popular believe, did not reveal antidiabetic activity to SC.

【 授权许可】

CC BY-NC   
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