The role of gadoxetic acid as a paramagnetic contrast medium in the characterization and detection of focal liver lesions: a review

Radiologia Brasileira

Renata Lilian Bormann¹  Eduardo Lima Da Rocha¹  Marcelo Longo Kierzenbaum¹  Bruno Cheregati Pedrassa¹  Lucas Rios Torres¹  Giuseppe D'ippolito¹ 

关键词: Magnetic resonance imaging;    Gadolinium;    Liver;    Contrast media;    Ressonância magnética;    Gadolínio;    Fígado;    Meios de contraste;   

DOI  :  10.1590/0100-3984.2013.1794

来源: SciELO

【 摘 要 】

Recent studies have demonstrated that the use of paramagnetic hepatobiliary contrast agents in the acquisition of magnetic resonance images remarkably improves the detection and differentiation of focal liver lesions, as compared with extracellular contrast agents. Paramagnetic hepatobiliary contrast agents initially show the perfusion of the lesions, as do extracellular agents, but delayed contrast-enhanced images can demonstrate contrast uptake by functional hepatocytes, providing further information for a better characterization of the lesions. Additionally, this intrinsic characteristic increases the accuracy in the detection of hepatocellular carcinomas and metastases, particularly the small-sized ones. Recently, a hepatobiliary contrast agent called gadolinium ethoxybenzyl dimeglumine, that is simply known as gadoxetic acid, was approved by the National Health Surveillance Agency for use in humans. The authors present a literature review and a practical approach of magnetic resonance imaging utilizing gadoxetic acid as contrast agent, based on patients' images acquired during their initial experiment.

【 授权许可】

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