Value of renal cortical thickness as a predictor of renal function impairment in chronic renal disease patients

Radiologia Brasileira

Samia Rafael Yamashita¹  Augusto Castelli Von Atzingen¹  Wagner Iared¹  Alexandre Sérgio De Araújo Bezerra¹  Adriano Luiz Ammirati¹  Maria Eugênia Fernandes Canziani¹  Giuseppe D'ippolito¹ 

关键词: Ultrasonography;    Chronic renal disease;    Chronic renal failure;    Renal cortex;    Glomerular filtration rate;    Ultrassonografia;    Insuficiência renal crônica;    Córtex renal;    Taxa de filtração glomerular;   

DOI  :  10.1590/0100-3984.2014.0008

来源: SciELO

【 摘 要 】

Objective: To determine the presence of linear relationship between renal cortical thickness, bipolar length, and parenchymal thickness in chronic kidney disease patients presenting with different estimated glomerular filtration rates (GFRs) and to assess the reproducibility of these measurements using ultrasonography. Materials and Methods: Ultrasonography was performed in 54 chronic renal failure patients. The scans were performed by two independent and blinded radiologists. The estimated GFR was calculated using the Cockcroft-Gault equation. Interobserver agreement was calculated and a linear correlation coefficient (r) was determined in order to establish the relationship between the different renal measurements and estimated GFR. Results: The correlation between GFR and measurements of renal cortical thickness, bipolar length, and parenchymal thickness was, respectively, moderate (r = 0.478; p < 0.001), poor (r = 0.380; p = 0.004), and poor (r = 0.277; p = 0.116). The interobserver agreement was considered excellent (0.754) for measurements of cortical thickness and bipolar length (0.833), and satisfactory for parenchymal thickness (0.523). Conclusion: The interobserver reproducibility for renal measurements obtained was good. A moderate correlation was observed between estimated GFR and cortical thickness, but bipolar length and parenchymal thickness were poorly correlated.

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