Instrumental and ethical aspects of experimental research with animal models

Revista da Escola de Enfermagem da USP

Mirian Watanabe¹  Cassiane Dezoti Da Fonseca¹  Maria De Fatima Fernandes Vattimo¹ 

关键词: Animal experimentation;    Basic research;    Animal Care Committees;    Nursing;    Review;    Experimentación anima;    Investigación básica;    Comités de atención animal;    Enfermería;    Revisión;    Experimentação animal;    Pesquisa básica;    Comitês de Cuidado Animal;    Enfermagem;    Revisão;   

DOI  :  10.1590/S0080-623420140000100023

来源: SciELO

【 摘 要 】

Experimental animal models offer possibilities of physiology knowledge, pathogenesis of disease and action of drugs that are directly related to quality nursing care. This integrative review describes the current state of the instrumental and ethical aspects of experimental research with animal models, including the main recommendations of ethics committees that focus on animal welfare and raises questions about the impact of their findings in nursing care. Data show that, in Brazil, the progress in ethics for the use of animals for scientific purposes was consolidated with Law No. 11.794/2008 establishing ethical procedures, attending health, genetic and experimental parameters. The application of ethics in handling of animals for scientific and educational purposes and obtaining consistent and quality data brings unquestionable contributions to the nurse, as they offer subsidies to relate pathophysiological mechanisms and the clinical aspect on the patient.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License