Exploring the environmental diversity of kinetoplastid flagellates in the high-throughput DNA sequencing era

Memórias do Instituto Oswaldo Cruz

Claudia Masini D’avila-levy¹  Carolina Boucinha¹  Alexei Kostygov¹  Helena Lúcia Carneiro Santos¹  Karina Alessandra Morelli¹  Anastasiia Grybchuk-ieremenko¹  Linda Duval¹  Jan Votýpka¹  Vyacheslav Yurchenko¹  Philippe Grellier¹  Julius Lukeš¹ 

关键词: Kinetoplastea;    metagenomics;    metabarcoding;    taxonomy;    Trypanosomatida;   

DOI  :  10.1590/0074-02760150253

来源: SciELO

【 摘 要 】

The class Kinetoplastea encompasses both free-living and parasitic species from a wide range of hosts. Several representatives of this group are responsible for severe human diseases and for economic losses in agriculture and livestock. While this group encompasses over 30 genera, most of the available information has been derived from the vertebrate pathogenic genera Leishmaniaand Trypanosoma. Recent studies of the previously neglected groups of Kinetoplastea indicated that the actual diversity is much higher than previously thought. This article discusses the known segment of kinetoplastid diversity and how gene-directed Sanger sequencing and next-generation sequencing methods can help to deepen our knowledge of these interesting protists.

【 授权许可】

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