Serologic survey of West Nile virus in horses from Central-West, Northeast and Southeast Brazil

Memórias do Instituto Oswaldo Cruz

Jaqueline Raymondi Silva¹  Larissa Campos De Medeiros¹  Vinícius Pinho Dos Reis¹  Juliana Helena Chávez¹  Thiago Demarchi Munhoz¹  Gustavo Puia Borges¹  Otavio Augusto Brioschi Soares¹  Carlos Henrique Coelho De Campos¹  Rosângela Zacarias Machado¹  Cristiane Divan Baldani¹  Maria Luana Cristiny Rodrigues Silva¹  Joice Lara Maia Faria¹  Edson Elias Da Silva¹  Luiz Tadeu Moraes Figueiredo¹ 

关键词: West Nile virus;    Flavivirus;    Brazil;   

DOI  :  10.1590/0074-0276130052

来源: SciELO

【 摘 要 】

Since the emergence of West Nile virus (WNV) in North America in 1999, there have been several reports of WNV activity in Central and South American countries. To detect WNV in Brazil, we performed a serological survey of horses from different regions of Brazil using recombinant peptides from domain III of WNV. Positive samples were validated with the neutralisation test. Our results showed that of 79 ELISA-positive horses, nine expressed WNV-specific neutralising antibodies. Eight of the infected horses were from the state of Mato Grosso do Sul and one was from the state of Paraíba. Our results provide additional evidence for the emergence of WNV in Brazil and for its circulation in multiple regions of the country.

【 授权许可】

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