The prevalence of human cytomegalovirus DNA in gliomas of Brazilian patients

Memórias do Instituto Oswaldo Cruz

Renata Fragelli Fonseca²  Marcia Tie Kawamura²  José Antônio Oliveira¹  Anselmo Teixeira¹  Gilda Alves¹  Maria Da Glória Da Costa Carvalho² 

[1] ,Universidade Federal do Rio de Janeiro Instituto de Biofísica Carlos Chagas Filho Laboratório de Controle da Expressão GênicaRio de Janeiro RJ ,Brasil

关键词: brain tumour;    glioma;    cytomegalovirus;    HCMV;   

DOI  :  10.1590/S0074-02762012000700020

来源: SciELO

【 摘 要 】

Members of the Herpesviridae family have been implicated in a number of tumours in humans. At least 75% of the human population has had contact with cytomegalovirus (HCMV). In this work, we screened 75 Brazilian glioma biopsies for the presence of HCMV DNA sequences. HCMV DNA was detected in 36% (27/75) of the biopsies. It is possible that HCMV could be a co-factor in the evolution of brain tumours.

【 授权许可】

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