Full-length genomic sequence of hepatitis B virus genotype C2 isolated from a native Brazilian patient

Memórias do Instituto Oswaldo Cruz

Mónica Viviana Alvarado-mora²  Rúbia Anita Ferraz Santana¹  Roberta Sitnik¹  Paulo Roberto Abrão Ferreira¹  Cristovão Luís Pitangueira Mangueira¹  Flair José Carrilho²  João Renato Rebello Pinho² 

[1] ,Universidade de São Paulo Faculdade de Medicina Instituto de Medicina TropicalSão Paulo SP ,Brasil

关键词: hepatitis B virus;    genotype C2;    China;    Bayesian analyses;    complete genome;    Brazilian patient;   

DOI  :  10.1590/S0074-02762011000400017

来源: SciELO

【 摘 要 】

The hepatitis B virus (HBV) is among the leading causes of chronic hepatitis, cirrhosis and hepatocellular carcinoma. In Brazil, genotype A is the most frequent, followed by genotypes D and F. Genotypes B and C are found in Brazil exclusively among Asian patients and their descendants. The aim of this study was to sequence the entire HBV genome of a Caucasian patient infected with HBV/C2 and to infer the origin of the virus based on sequencing analysis. The sequence of this Brazilian isolate was grouped with four other sequences described in China. The sequence of this patient is the first complete genome of HBV/C2 reported in Brazil.

【 授权许可】

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