Identification of hepatitis C virus subtype 2c by sequencing analysis in patients from Córdoba, Argentina

Memórias do Instituto Oswaldo Cruz

Viviana Ré²  Marta Contigiani²  Clara Fumiko Tachibana Yoshida¹  Elisabeth Lampe¹ 

[1] ,Universidad Nacional de Córdoba Facultad de Ciencias Médicas Instituto de Virologia Dr. J. M. VanellaCórdoba,Argentina

关键词: Hepatitis C Virus;    Argentina;    HCV subtype 2c;   

DOI  :  10.1590/S0074-02762007000800016

来源: SciELO

【 摘 要 】

In Argentina, most information on hepatitis C virus (HCV) genotype distribution comes from studies carried out in Buenos Aires (east province). In order to identify HCV subtypes in central Argentina, nucleotide sequencing of core region was performed in samples from 36 patients living in Córdoba, the second most populated province of Argentina. The sequence analysis identified subtype 2c as the most prevalent (50%), followed by subtype 1b (33%) and to a lesser extent by subtypes 1a (11%), 3a (3%) and 4a (3%). This is the first report of circulation of HCV subtype 2c in this region of Argentina and also such high prevalence has never been found before in the genotype distribution of South America.

【 授权许可】

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