Leishmania (Viannia) lainsoni: occurrence of intracellular promastigote forms in vivo and in vitro

Memórias do Instituto Oswaldo Cruz

José R Corrêa¹  Maurilio J Soares¹ 

[1] ,Fiocruz Instituto Oswaldo Cruz Departamento de Ultra-estrutura e Biologia CelularRio de Janeiro RJ ,Brasil

关键词: Leishmania;    lesion;    macrophage;    ultrastructure;   

DOI  :  10.1590/S0074-02762006000800016

来源: SciELO

【 摘 要 】

Experimental chronic (45-day-old) skin lesion in hamster hind foot induced by Leishmania (Viannia) lainsoni infection showed the presence of promastigote forms in the tissue, inside parasitophorous vacuoles, as assessed by transmission electron microscopy. Experimental in vitro interaction (24 and 48 h) between Leishmania (V.)lainsoni and J774-G8 macrophage cells also demonstrated the same profile. This morphological aspect is unusual, since in this parasite genus only amastigote forms have been described as the resistant and obligate intracellular forms.

【 授权许可】

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