Physiological changes in Biomphalaria glabrata say, 1818 (Pulmonata: Planorbidae) caused by sub-lethal concentrations of the latex of Euphorbia splendens var. hislopii N.E.B (Euphorbiaceae)

Memórias do Instituto Oswaldo Cruz

Clélia Christina Mello-silva²  Maurício Carvalho De Vasconcellos¹  Jairo Pinheiro¹  Maria De Lurdes De Azevedo Rodrigues² 

[1] ,Universidade Federal Rural do Rio de Janeiro Departamento de Parasitologia Animal Seropédica RJ ,Brasil

关键词: plant molluscide;    Euphorbia splendens var. hislopii;    Biomphalaria glabrata;   

DOI  :  10.1590/S0074-02762006000100002

来源: SciELO

【 摘 要 】

Molluscides have been used as one of the strategies to control schistosomiasis. Many plant extracts with molluscidal effects have been tested, but the action of the latex of Euphorbia splendens var. hislopii is considered the most promising because it meets the recommendations of the World Health Organization (WHO). The objective of this study was to determine the lethal dose and identify the effects of the different doses of latex of E. splendens var. hislopii on the physiology of Biomphalaria glabrata submitted to treatment for 24 h. The concentrations of glucose, uric acid and total proteins in the hemolymph and of glycogen in the digestive gland and cephalopodal mass were determined. The LD50 value was 1 mg/l. The highest escape index was found to be at a concentration of 0.6 mg/l. The results showed that the latex of E. splendens var. hislopii caused a sharp reduction in the reserves of glycogen in the digestive gland and elevation of the protein content in the hemolymph of B. glabrata.

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