Evaluation of tests based on the antibody response to keyhole limpet haemocyanin and soluble egg antigen to differentiate acute and chronic human schistosomiasis mansoni

Memórias do Instituto Oswaldo Cruz

Lílian Beck¹  Daniele Sm Van-lüme²  Joelma R De Souza²  Clarice N Lins De Morais²  Wlademir G Melo²  Edeneide Xavier²  Constança S Barbosa²  Marcílio L Aroucha¹  Ana Lúcia C Domingues¹  Tereza Favre¹  Otávio Pieri¹  Frederico Gc Abath²  Silvia Ml Montenegro² 

[1] ,Fiocruz Centro de Pesquisas Aggeu Magalhães Laboratório de Bioquímica e Biologia MolecularRecife PE ,Brasil

关键词: keyhole limpet haemocyanin;    soluble egg antigens;    enzime-linked immunosorbent assay;   

DOI  :  10.1590/S0074-02762004000900017

来源: SciELO

【 摘 要 】

Specific IgG and IgM responses to soluble egg antigen (SEA) and keyhole limpet haemocyanin (KLH) were measured by ELISA in patients with acute and chronic schistosomiasis. The tests based upon IgM and IgG antibodies responses to KLH presented the best diagnostic discrimination, and can be used in conjunction with clinical and epidemiological data to the differential diagnosis of acute schistosomiasis.

【 授权许可】

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