Ivermectin resistant and susceptible third-stage larvae of Haemonchus contortus: cholinesterase and phosphatase activities

Memórias do Instituto Oswaldo Cruz

Consuelo Giménez-pardo¹  Maria Mercedes Martínez-grueiro²  Alicia Gómez-barrio²  Filomena Rodríguez-caabeiro¹ 

[1] ,Universidad de Alcalá Facultad de Farmacia Departamento de Microbiología y ParasitologíaMadrid,España

关键词: Haemonchus contortus;    cholinesterase;    phosphatase;    ivermectin;    resistant;   

DOI  :  10.1590/S0074-02762004000200019

来源: SciELO

【 摘 要 】

Cholinesterase and acid phosphatase (AP), but not alkaline phosphatase activities, were detected in cytosolic and membrane-bound fractions of ivermectin resistant and susceptible Haemonchus contortus infective-stage larvae. Some differences in acetylcholinesterase activity of cytosolic fractions and in the AP activity of these fractions as well as in the response to AP inhibitors by membrane-bound fractions were detected. Data are discussed.

【 授权许可】

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