A comparative parasitologic study on Biomphalaria glabrata snail and C3H/He mice infected with human and murine isolates of Schistosoma mansoni derived from Sumidouro, Rio de Janeiro, Brazil

Memórias do Instituto Oswaldo Cruz

Nilcéa Freire²  Rosângela Rodrigues-silva¹  José Roberto Machado-silva²  Luís Rey¹ 

[1] ,Universidade do Estado do Rio de Janeiro Faculdade de Ciências Médicas Departamento de Patologia e LaboratóriosRio de Janeiro RJ ,Brazil

关键词: Schistosoma mansoni;    human and murine isolates;    host-parasite relationship;    snail;    C3H/He mice;    Rio de Janeiro;    Brazil;   

DOI  :  10.1590/S0074-02762003000600013

来源: SciELO

【 摘 要 】

Experiments were carried out to analyze the biological characteristics of two sympatric isolates of Schistosoma mansoni derived from humans and murines in a low endemic transmission area (Sumidouro county, state of Rio de Janeiro, Brazil). Sympatric reared-laboratory Biomphalaria glabrata and C3H/He mice were used as experimental hosts. Parameters assessed comprised: precercarial period, infectivity and mortality (snails), prepatent period, infectivity (percentage of cercariae maturation into adult worm) and intestinal egg count (mice). The murine isolate showed a shorter precercarial period and higher infectivity than human isolate (p < 0.05). This biological heterogenicity did not correspond to the vertebrate data because any biological parameter presented significant difference (p > 0.05). These data suggest that both isolates are local sub-populations, providing support for the hypotheses that in a same biotope mixed populations or sub-populations circulate among their main host (human beings) and/or rodent as an anfixenous infection.

【 授权许可】

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