Screening of some plants used in the Brazilian folk medicine for the treatment of infectious diseases

Memórias do Instituto Oswaldo Cruz

Fabíola Barbiéri Holetz²  Greisiele Lorena Pessini²  Neviton Rogério Sanches²  Diógenes Aparício Garcia Cortez¹  Celso Vataru Nakamura¹  Benedito Prado Dias Filho¹ 

[1] ,Universidade Estadual de Maringá Programa de Pós-graduação em Ciências Farmacêuticas

关键词: medicinal plants;    antibacterial activity;    anticandidal activity;    bioautography;   

DOI  :  10.1590/S0074-02762002000700017

来源: SciELO

【 摘 要 】

Extracts of 13 Brazilian medicinal plants were screened for their antimicrobial activity against bacteria and yeasts. Of these, 10 plant extracts showed varied levels of antibacterial activity. Piper regnellii presented a good activity against Staphylococus aureus and Bacillus subtilis, a moderate activity on Pseudomonas aeruginosa, and a weak activity against Escherichia coli. Punica granatum showed good activity on S. aureus and was inactive against the other standard strains. Eugenia uniflora presented moderate activity on both S. aureus and E. coli. Psidium guajava,Tanacetum vulgare, Arctium lappa, Mikania glomerata, Sambucus canadensis, Plantago major and Erythrina speciosa presented some degree of antibacterial activity. Spilanthes acmella, Lippia alba, and Achillea millefolium were considered inactive. Five of the plant extracts presented compounds with Rf values similar to the antibacterial compounds visible on bioautogram. Of these, three plants belong to the Asteraceae family. This may mean that the same compounds are responsible for the antibacterial activity in these plants. Anticandidal activity was detected in nine plant extracts (P. guajava, E. uniflora, P. granatum, A. lappa, T. vulgare, M. glomerata, L. alba, P. regnellii, and P. major). The results might explain the ethnobotanical use of the studied species for the treatment of various infectious diseases.

【 授权许可】

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