Palaearctic origin of Leishmania

Memórias do Instituto Oswaldo Cruz

Sara F Kerr¹ 

[1] ,University of the Incarnate WordSan Antonio Texas ,USA

关键词: Leishmania mexicana;    Leishmania major;    Endotrypanum;    Sauroleishmania;    Sigmodontinae;    Muridae;    Lutzomyia;    Phlebotomus;    Sergentomyia;    coevolution;    biogeography;   

DOI  :  10.1590/S0074-02762000000100011

来源: SciELO

【 摘 要 】

The hypothesis of a Palaearctic origin of Leishmania in the early Cenozoic, dispersal to the Nearctic in the late Eocene and to the Neotropical in the Pliocene is presented. It is further hypothesized that murid rodents and their immediate ancestors have been important mammalian reservoirs since the origination of Leishmania. Biochemical, molecular, biogeographical, entomological, mammalalogical and ecological support for these hypotheses are reviewed.

【 授权许可】

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